Roles of ESCRT in autophagy-associated neurodegeneration
نویسندگان
چکیده
منابع مشابه
ESCRT, autophagy, and frontotemporal dementia.
Many age-dependent neurodegenerative diseases are associated with the accumulation of abnormally folded proteins within neurons. One of the major proteolytic pathways in the cell is the autophagy pathway, which targets cytoplasmic contents and organelles to the lysosomes for bulk degradation under various physiological and stressful conditions. Although the importance of autophagy in cellular p...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2008
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.5384